Author profile

Prof Jack A. Tuszynski, PhD

Scientific Director · Allard Chair in Oncology, University of Alberta · Scientific Director, Open Source Medicine Foundation

Jack A. Tuszynski

Scientific Director

Prof Jack A. Tuszynski, PhD

Allard Chair in Oncology, University of Alberta · Scientific Director, Open Source Medicine Foundation

Jack is the Allard Chair in Oncology at the University of Alberta and one of the world's leading computational biophysicists. With approximately 400 peer-reviewed publications, his expertise spans tubulin biology, motor proteins, computational drug design, systems biology, and photobiomodulation.

His academic research spans computational and AI-assisted drug discovery, with deep expertise in systems biology approaches to cancer and neurodegeneration.

As Scientific Director he reviews the Foundation's research notes before publication.

Articles reviewed by this author

Research notes are plain-language summaries of peer-reviewed publications. See all research notes.

Selected publications

  1. Vottero P, Centroni M, Gitari E, Winter P, Tuszynski J, Aminpour M. Molecular simulations of paclitaxel binding to mutant β-tubulin: insights into chemotherapy resistance. Journal of Computer-Aided Molecular Design. 2026;40(1):17.
  2. Halma M, Hassaan S, Tuszynski JA. Alleviating age-related disease burden. Frontiers in Aging. 2026;7:1828980.
  3. Ashrafuzzaman M, Tuszynski JA. Molecular Simulations of Biomembranes: From Biophysics Fundamentals to Biological Function. Membranes. 2026;16(3):80.
  4. Zattoni J, Ludueña RF, Aminpour M, Tuszynski JA. Computational discovery of potential therapeutic agents against brain-eating amoeba (Naegleria fowleri). PLOS ONE. 2025;20(7):e0327621.
  5. Loreti G, Vottero P, Olivetti EC, Vezzetti E, Tuszynski J, Marcolin F, et al. Delineating SARS-CoV-2 spike protein and antibodies interaction interfaces via siamese neural networks: A geometric and image-based analysis. PLOS ONE. 2025;20(11):e0335270.
  6. Lim L, Staelens MA, Truglia B, Lazzari DD, Gregorio ED, Shankar K, et al. Beyond Gamma: Synergistic Potential of 10 Hz Alpha and 40 Hz Gamma Photobiomodulation in Alzheimer's Disease Treatment. Alzheimer's & Dementia. 2025;21:e105314.
  7. Truglia B, Castria S, Brown D, Lim L, de Wever B, Lewis J, Tuszynski JA. Effects of Light-Induced Electromagnetic Fields on Human Cancer Cells in Vitro. Bioelectricity. 2025;7(3):193-198.

Representative recent entries transcribed from the Google Scholar export (PDF, 63 pages); see Google Scholar for the complete list.

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