Open Source Medicine
Open Source Medicine is a research organization that advances independent medicine through rigorous, peer-reviewed science—delivering evidence-based solutions from bench to bedside.
Open Source Medicine is a research organization that advances independent medicine through rigorous, peer-reviewed science—delivering evidence-based solutions from bench to bedside.
Building the infrastructure to transform basic science discoveries into clinical solutions for healthcare transformation
Molecular mechanisms, biophysical modeling, computational analysis
Evidence synthesis, therapeutic target identification, protocol development
Protocol testing, RCT design, real-world evidence generation
Guideline development, policy influence, clinical implementation
Our foundation in molecular biophysics—including optical tweezers, single-molecule techniques, and RNA structure analysis—enables us to understand disease mechanisms at the fundamental level. This scientific rigor translates to more robust therapeutic hypotheses.
We don't just observe clinical outcomes—we understand why interventions work. Our research connects molecular pathways (mitochondrial dysfunction, spike protein pathology, metabolic dysregulation) to therapeutic strategies.
Through collaborations with world-class computational biophysicists, we leverage in silico drug discovery, molecular dynamics simulations, and predictive modeling to accelerate therapeutic development.
Our multi-site clinical research network enables rapid translation from bench to bedside. We're positioned to validate therapeutic protocols through rigorous Phase II/III trials with real patient outcomes.
Our distributed research infrastructure spans three continents, enabling specialized expertise and collaborative innovation
Roatan & Tegucigalpa — Clinical Research Hub
Italy — Biophysics Center
Canada — Biophysics & Virology
Traditional pharmaceutical development is slow, expensive, and often disconnected from patient needs. Our end-to-end pipeline addresses this by:
World-class scientists driving independent medical research across biophysics, integrative medicine, and translational science
Director of Scientific Research
Matthew Halma leads Open Source Medicine's scientific research division. His work spans molecular biology, viral RNA structure, cancer metabolism, and post-viral pathology. With peer-reviewed publications in landmark journals including PNAS and Nature Communications, he has established Open Source Medicine as a credible force in integrative medicine research. His research on PACVS therapeutic protocols and pharmacovigilance methodology (DARE-SAFE) is shaping evidence-based approaches to post-vaccine injury.
Senior Research Collaborator
Professor Tuszynski is a distinguished physicist and biophysicist with dual appointments at the University of Alberta (Canada) and Politecnico di Torino (Italy). A prolific researcher with expertise in computational biophysics, cancer research, and drug discovery, he has co-authored 8-10 papers with Open Source Medicine across cancer metabolism, aging, and integrative medicine. His collaboration brings world-class computational modeling and access to cutting-edge research facilities to Open Source Medicine's translational programs.
Accelerate your research agenda with Open Source Medicine's end-to-end scientific support—from concept to peer-reviewed publication
Open Source Medicine provides comprehensive contract research and publication services for pharmaceutical companies, biotech startups, nutraceutical brands, health systems, and foundations seeking rigorous, independent scientific validation of their products, protocols, or therapeutic approaches.
Comprehensive literature synthesis following PRISMA guidelines to evaluate evidence for your therapeutic claims, ingredients, or interventions.
Expert-authored review articles synthesizing the state of science for your therapeutic domain, product category, or clinical approach.
Design and execution of clinical studies, observational research, and mechanistic investigations to generate novel evidence.
Leverage our biophysics expertise for molecular modeling, drug-target interaction analysis, and predictive computational studies.
40+ peer-reviewed papers in journals including PNAS, Nature Communications, Heliyon (Cell Press), and Frontiers. Your research benefits from our established credibility and journal relationships.
Our team consistently publishes in top-quartile (Q1) journals with impact factors 5–17. We navigate the peer review process efficiently, maximizing acceptance rates.
Unlike marketing-driven research firms, we bring fundamental scientific rigor. Our biophysics foundation enables us to explain why interventions work at the molecular level.
As a 501(c)(3) nonprofit research organization, Open Source Medicine provides conflict-free scientific assessment. Our independence enhances the credibility of findings for regulators, clinicians, and consumers.
Specialized expertise in herbal medicine, nutraceuticals, metabolic interventions, and integrative protocols—domains often underserved by traditional CROs.
From single publication projects to multi-year research partnerships, we structure engagements to match your budget, timeline, and strategic objectives.
Project scoping is complimentary. We develop customized proposals based on your research objectives, timeline, and publication goals. Typical engagements range from $15,000 (narrative review) to $150,000+ (multi-site clinical study with publication).
Request a Research Consultation →Let's discuss how Open Source Medicine can support your evidence generation and publication goals.